Posted by Laura Johnston Illustration 2016


Nerve  - Petite Graphics

Pain is a pain to learn!

After reading an article about the release of a new compound to combat pain, I decided to create an image to illustrate this article (Structure-based discovery of opioid analgesics with reduced side effects). Little did I know what I was getting myself into! (March 2017 - finished part one, check it out!)

As with many of my side projects, I find it necessary to get some background information in order to better understand the science behind the original article. This led me to look at numerous papers and articles that examined some of the biology, issues, and history about pain relief. To paraphrase Socrates, the more I learn, the less I know. Meaning, each article seemed to lead to more questions.

Nonetheless, I have created several illustrations exploring the mechanisms behind pain and opioids. However, I thought I start with this image, similar to the one I posted on Behance.

Pain Petite Graphics

  • Structure-based discovery of opioid analgesics with reduced side effects. Nature. 2016 Aug 17;537(7619):185-190. doi: 10.1038/nature19112. Manglik A, Lin H, Aryal DK, McCorvy JD, Dengler D, Corder G, Levit A, Kling RC, Bernat V, Hübner H, Huang XP, Sassano MF, Giguère PM, Löber S, Da Duan, Scherrer G, Kobilka BK, Gmeiner P, Roth BL, Shoichet BK.
  • Opioid Receptors. Christoph Stein Annu. Rev. Med. 2016. 67:433–51
  • Opioid receptors. John McDonald,and DG Lambert. Contin Educ Anaesth Crit Care Pain (2005) 5 (1): 22-25.
  • http://thebrain.mcgill.ca/avance.php